Rivers, estuaries, deltas and coastal seas connect over three quarters of the Earth’s land surface with the ocean. This connection is essential for humankind, providing key ecosystem services for food, water and transport. However, these connections are increasingly threatened, impacted by global changes that affect entire River-Sea Systems worldwide. Urgent action is needed to align how we use these River-Sea systems, and how we protect them for the future. DANUBIUS-RI is designed to enable information service development, and help communities access the needed knowledge. Through the DANUBIUS-RI Hub, you can explore River-Sea systems using our pan-European network of thematic nodes, supersites for testing, e-Learning and Technology Transfer resources, and our data centre. Working with us, we bring the right people to you, enabling your efforts to tackle issues such as landscape fragmentation, river regulation and damming, water and sediment abstraction, eutrophication and pollution, the loss of biodiversity and the spread of invasive species. Our goal is to equip communities with the information services and knowledge, to help them counter the effects of climate change, and turn the tide on unsustainable use of their River-Sea Systems.