Climate change, population growth and antimicrobial resistance have led to the emergence of new microbes and the transformation of previously controlled diseases. Municipal wastewater is a source of various markers that reflect comprehensive unbiased health information of the entire community. Wastewater-Based Surveillance (WBS) is a new scientific tool with the potential to act as a complementary approach to monitoring a number of variables such as local pathogens and clinically important indicators. The same contaminants that are monitored in wastewater from a human health perspective make it difficult to recycle the vital nutrients in the wastewater sludge. The infrastructure implemented is expected to promote the necessary measures for high-quality research, digital and green transition and growth. In addition, the solutions are globally scalable.